Human Genome Project started in 1990 by US department of energy and national institute of health and completed in 2003 .
It was associated biolnformatics .
A genome constitute haploid set of chromosomes in a cell
Example - Human genome is packed in 23 pairs of chromosomes .
The main objectives of HGP was to develop gene mapping technique to identify gene having error to store information in database and develop DNA analysis tools and techniques to develop industrial technology .
A human genome contains 3164.7 millions bases bases .
The average gene consists of 300 bases . The largest known gene in human dystrophin with 2,4 million bases.
The total number of gene is estimated to be 30000 and 99.9 bases are exactly same in all people .
Less that 2 percent genome codes for protein and human genome contain larger repetitive sequence .The repetitive sequence dont take part in coding but have and impact KN chromosome structure dynamics and evolution .
Chromosome 1 contains most genes with 2968 number of genes where as chromosomes y contain fewest with 23 genes
1.4 millions location are identifies in human genome where single base DNA sequence present .It is known as single nucleotide poly morphins .
APPLICATION
It can be used in disease administration and identifying gene causing disorder .
Disease can be studied in molecular level with therapeutic procedure .
It can be used in analysi of evolutionary relationship between human and its close relatives relations like primates mammals .
It is used to identify difference between two ethane groups.
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