Sunday, 22 August 2021

FEATURES OF DOUBLE HELICAL STRUCTURE OF DNA

A normal DNA molecule contain two polynucleotide chains twisted around each other .

Each chain has two ends 5' end occupied with phosphate group and 3' end with hydroxy group .

DNA stands are anti parallel i.e. one strand 5' to 3' direction.

The long polynucleotide chain consists of several nucleotides i.e. deoxy ribo-neucleotide .Each nucleotide made up of a phosphate group a sugar and nitrogenous base .

Pentose sugar present in DNA is a deoxy ribose sugar phosphodiester bonds are formed between 5' carbon of sugar of one nucleotide and 3' carbon of sugar of the next nucleotide .

Nitrogenous base is attached to at 1' carbon of sugar . At this place purine base is attached by its 9' position and pyrimidine by its 3' position . The nitrogenous bases are attached to sugar by N-glycosidic bone. 

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