Tuesday, 6 July 2021

GENE THERAPY

 It is the clinical therapy of manipulating the genes to treat the genetic disorders.

In this therapy the faulty or non-functional genes are replaced by the functional gene .

The gene therapy is two type 

1- Germline gene therapy 

2 - Somatic cell gene therapy 

Germline gene therapy - The germ cell i.e. sperm and ova are modified by the introduction of functional genes.

Somatic cell gene - The functional gene is introduced only in somatic cell .

Example of gene therapy are;

The first clinical gene therapy was given in 1990 to a four year old girl with ADA .

Most common gene therapy is GENEAUGMENTATION THERAPY 

The over production of proteins to use GENE INHIBITION THERAPY .

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