It is the amount of lactose present in a bacterial cell .
It consist two condition
I - Switch on condition
When lactose amount is less in bacterial cell .
RNA polymerase binds to promoter to initiate expression .
Regulatory gene synthesis repressor protein . This protein comes and binds to operator region .
Asa result confirmation of operator changes and it blocks RNA polymerase to move forward .
Transcription and translation cannot takes place so no enzyme formation in cell .
This condition is known as switch off condition .
II - Switch on condition
When lactose quantity increase in the cell .
Some of the lactose come and bind to repressor protein .As a result protein confirmation changes .
Due to change is confirmation operators get unblocked .
RNA polymerase moves forward and transcription and translation occur .
structure genes lac A synthesis transacetylase lac Y permease and lac Z galactosidase .
This condition is known as switch on condition.
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